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The US has surpassed the national tally of China with coronavirus cases standing at over 85,000.
It comes as over 519,000 tests were administered across many states, with the death toll rising beyond 1,200.
New York, New Orleans and other cities have seen an increase in hospitalisations, with many centres reporting shortages of supplies, staff and sick beds.
It comes President Donald Trump set up a "Easter deadline" for the country to return to work.
Meanwhile, China has recorded more than 81,000 cases, with Italy next on the tally with 80,589 cases.
The global tally has crossed 500,000, with more than 124,000 recoveries and over 24,000 deaths.
U.S. Attorney General Pamela Bondi directed federal prosecutors to seek the death penalty for Luigi Mangione, the man accused of shooting and killing the CEO of UnitedHealth Group's insurance division Brian Thompson in New York last year.
Aid groups in Myanmar on Tuesday described scenes of devastation and desperation after an earthquake that killed more than 2,700 people, stressing an urgent need for food, water and shelter and warning the window to find survivors was fast closing.
The Trump administration has fired staff at U.S. health agencies including the Centers for Disease Control and Prevention, Food and Drug Administration and National Institutes of Health, as it embarked on its plan to cut 10,000 health jobs, according to sources familiar with the situation and a health official.
The Israeli military said it killed a Hezbollah operative in an airstrike on Beirut's southern suburbs early on Tuesday, while three other people were reported killed and seven injured, further testing a shaky four-month ceasefire between Israel and Hezbollah.
President His Highness Sheikh Mohamed bin Zayed Al Nahyan today offered his condolences to His Highness Sheikh Saud bin Rashid Al Mualla, Supreme Council Member and Ruler of Umm Al Quwain, on the death of his mother, Sheikha Hessa bint Humaid bin Abdul Rahman Al Shamsi.
The UAE’s National Ambulance Service handled 22,903 cases across the country in the first quarter of this year, according to the National Guard Command.
H.H. Sheikh Saud bin Rashid Al Mualla, Supreme Council Member and Ruler of Umm Al Qaiwain, received condolences on the passing of his mother, the late Sheikha Hessa bint Hamid bin Abdulrahman Al Shamsi, at the condolence majlis held at the Emiri Court.